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Clonal evolution of tumours

Tumors are usually of clonal origin, that is, they arise from a single cell. The monoclonality of tumors can be seen, for example, in multiple myeloma, a tumor of the plasma cells. In serum protein electrophoresis, antibodies migrate mainly in the gamma globulin fraction. Antibodies are...

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Video

Molecular action of p53 in carcinogenesis

The tumor suppressor protein p53 is a transcription factor. p53 monomers assemble into tetramers that bind to consensus sequences in the DNA and activate the transcription of p53 response genes. P53 target genes are involved in the regulation of proliferation, apoptosis and genomic...

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Layout A

Video

Clonal evolution of tumours

Tumors are usually of clonal origin, that is, they arise from a single cell. The monoclonality of tumors can be seen, for example, in multiple myeloma, a tumor of the plasma cells. In serum protein electrophoresis, antibodies migrate mainly in the gamma globulin fraction. Antibodies are...

Read More
Video

Molecular action of p53 in carcinogenesis

The tumor suppressor protein p53 is a transcription factor. p53 monomers assemble into tetramers that bind to consensus sequences in the DNA and activate the transcription of p53 response genes. P53 target genes are involved in the regulation of proliferation, apoptosis and genomic...

Read More

Layout B

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