The MAPK pathway is dysregulated in more than 50 % of all human tumors. The pathway starts with the activation of a receptor tyrosine kinase, which transmits the signal...
Archive - September 2021
The second messenger PIP3 formed by PI3K can be hydrolyzed to PIP2 by the phosphatase PTEN. PIP2 can be hydrolyzed to diacyl glycerol (DAG) and inositol trisphosphate...
Receptor tyrosine kinases transmit signals from outside the cell via the membrane into the cytosol. After activation by an external factor, the receptor monomers...
The cell goes through typical stages between two cell divisions. The successive phases can be visualized as the so-called cell cycle. The cell cycle comprises two main...